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Interaction of glutamate- and adenosine-induced decrease of acetylcholine quantal release at frog neuromuscular junction
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SYSNO ASEP 0355368 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Interaction of glutamate- and adenosine-induced decrease of acetylcholine quantal release at frog neuromuscular junction Author(s) Adámek, S. (CZ)
Shakirzyanova, V. (RU)
Malomouzh, A. I. (RU)
Naumenko, N. V. (RU)
Vyskočil, František (FGU-C) RIDSource Title Physiological Research. - : Fyziologický ústav AV ČR, v. v. i. - ISSN 0862-8408
Roč. 59, č. 5 (2010), s. 803-810Number of pages 8 s. Language eng - English Country CZ - Czech Republic Keywords Endplate potentials ; Guanylyl cyclase Subject RIV ED - Physiology R&D Projects IAA500110905 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) GA202/09/0806 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000284489300019 Annotation The depression of nerve stimulation evoked number of quanta (EPC) by glutamate was removed by inhibition of the NO production in the muscle and the NO cascade is common post-receptor pathway started by both glutamate and adenosine presynaptic receptors. Spontaneously released quanta (MEPCs) are not regulated by NO cascade in the presence of glutamate and its specific effect on the evoked release points to modulation (phosphorylation) of the voltage-dependent Ca2+ channels at the release zone that are necessary for evoked quantal release during nerve stimulation Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2011
Number of the records: 1