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Enhancement of Thymoquinone Concentration in Black Cumin Extract Using Supercritical Fluid Fractionation
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SYSNO ASEP 0355265 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Enhancement of Thymoquinone Concentration in Black Cumin Extract Using Supercritical Fluid Fractionation Author(s) Sajfrtová, Marie (UCHP-M) RID, ORCID, SAI
Topiař, Martin (UCHP-M) RID, ORCID, SAI
Karban, Jindřich (UCHP-M) RID, ORCID, SAI
Sovová, Helena (UCHP-M) RID, ORCID, SAISource Title Proceedings. - Salerno : Centro Stampa di Ateneo, 2010 / Reverchon E. - ISBN 88-7897-040-9 Pages s. 127-132 Number of pages 6 s. Publication form CD-ROM - CD-ROM Action Conference on Supercritical Fluids and Their Applications /9./ Event date 05.09.2010-08.09.2010 VEvent location Sorrento Country IT - Italy Event type WRD Language eng - English Country IT - Italy Keywords supercritical fluid extraction ; thymoquinone ; carbon dioxide Subject RIV CI - Industrial Chemistry, Chemical Engineering R&D Projects GA525/08/1179 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z40720504 - UCHP-M (2005-2011) Annotation Supercritical fluid extraction (SFE) using carbon dioxide has been studied as a modern, environmentally friendly method to separate high-added value compounds from plants that allows dissolving preferably the required compounds by changing extraction conditions. SFE helps to obtain extracts with both TQ concentration and biological activity significantly higher than those isolated by conventional separation methods. This work is focused on TQ from black cumin seeds. To obtain higher concentration of the desired compound, SFE was applied with consequent fractionation of the extract in two separators maintained at different pressure and temperature. The efficiency of SFE in terms of TQ concentration in extract and yield was compared with the products of hydrodistillation and Soxhlet extraction. Workplace Institute of Chemical Process Fundamentals Contact Eva Jirsová, jirsova@icpf.cas.cz, Tel.: 220 390 227 Year of Publishing 2011
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