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GABA-B receptor antagonist CGP 35348 interferes with an arrest of cortical epileptic afterdischarges in developing rats

SYSNO ASEP	0354870
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	GABA-B receptor antagonist CGP 35348 interferes with an arrest of cortical epileptic afterdischarges in developing rats
Author(s)	Mareš, Pavel (FGU-C)_{RID, ORCID}
Source Title	Epilepsy Research. - : Elsevier - ISSN 0920-1211 Roč. 92, 2-3 (2010), s. 125-133
Number of pages	9 s.
Language	eng - English
Country	NL - Netherlands
Keywords	seizures ; cortex ; ontogeny
Subject RIV	FH - Neurology
R&D Projects	GA305/05/2581 GA ČR - Czech Science Foundation (CSF)
	GAP304/10/1274 GA ČR - Czech Science Foundation (CSF)
	LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z50110509 - FGU-C (2005-2011)
UT WOS	000285657300002
DOI	10.1016/j.eplepsyres.2010.08.011
Annotation	Antagonist of GABA-B receptor exhibits marked proconvulsant action in cortical epileptic afterdischarges in immature rats. Thresholds for induction of epileptic seiyures are decreased and duration of seizures is markedly prolonged
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2011

Number of the records: 1