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Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced by Pseudallescheria boydii

SYSNO ASEP	0354251
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Characterization of Pseudacyclins A-E, a Suite of Cyclic Peptides Produced by Pseudallescheria boydii
Author(s)	Pavlásková, Kateřina (MBU-M) Nedvěd, Jan (MBU-M) Kuzma, Marek (MBU-M)_{ORCID, RID} Žabka, Martin (MBU-M) Šulc, Miroslav (MBU-M)_{RID, ORCID} Sklenář, Jan (MBU-M) Novák, Petr (MBU-M)_{RID, ORCID} Benada, Oldřich (MBU-M)_{ORCID, RID} Kofroňová, Olga (MBU-M)_{RID, ORCID} Hajduch, M. (CZ) Derrick, P.J. (NZ) Lemr, Karel (MBU-M)_{RID, ORCID} Jegorov, A. (CZ) Havlíček, Vladimír (MBU-M)_{RID, ORCID}
Source Title	Journal of Natural Products. - : American Chemical Society - ISSN 0163-3864 Roč. 73, č. 6 (2010), s. 1027-1032
Number of pages	6 s.
Language	eng - English
Country	US - United States
Keywords	EMERGING HUMAN PATHOGEN ; SCEDOSPORIUM-APIOSPERMUM ; ASPERGILLUS-FUMIGATUS
Subject RIV	EE - Microbiology, Virology
R&D Projects	LC07017 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z50200510 - MBU-M (2005-2011)
UT WOS	000279070300001
DOI	10.1021/np900472c
Annotation	Two Pseudallescheria boydii isolates have been identified as being producers of cyclic peptides. Five putative nonribosomal peptides with a unique structure, which have been named pseudacyclins, were characterized by nuclear magnetic resonance spectroscopy and mass spectrometry. The most abundant representative of the pseudacyclins was quantified also on fungal spores. The presence of these peptides on inhaled fungal spores creates the possibility for exploitation of pseudacyclins as early indicators of fungal infections caused by Pesudallescheria species
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2011

Number of the records: 1