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New predictive model for monitoring bone remodeling
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SYSNO ASEP 0353375 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title New predictive model for monitoring bone remodeling Author(s) Bougherara, H. (US)
Klika, Václav (UT-L) RID
Maršík, František (UT-L) RID
Mařík, I. (CZ)
Yahia, L.H. (US)Number of authors 5 Source Title Journal of Biomedical Materials Research. Part A. - : Wiley - ISSN 1549-3296
95A, č. 1 (2010), s. 9-24Number of pages 16 s. Language eng - English Country US - United States Keywords bone remodeling ; open system thermodynamics ; bone biochemistry Subject RIV BJ - Thermodynamics R&D Projects GA106/03/1073 GA ČR - Czech Science Foundation (CSF) GA106/03/0958 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z20760514 - UT-L (2005-2011) UT WOS 000281448700002 DOI 10.1002/jbm.a.32679 Annotation The model is based on chemical kinetics and irreversible thermodynamic principles, in which bone is considered as a self-organizing system that exchanges matter, energy and entropy with its surroundings. The current model suggested that bone remodeling was a dynamic process which was driven by mechanical loading, metabolic factors and other external contributions. Furthermore, results of virtual computations of bone density in a composite femur showed the development of a dense cortical bone around the medullary canal and a dense trabeculae bone between the femoral head and the calcar region of the medial cortex due to compressive stresses. Workplace Institute of Thermomechanics Contact Marie Kajprová, kajprova@it.cas.cz, Tel.: 266 053 154 ; Jana Lahovská, jaja@it.cas.cz, Tel.: 266 053 823 Year of Publishing 2011
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