Number of the records: 1

A Versatile Synthesis of Functionalized Pentahelicenes

SYSNO ASEP	0353234
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	A Versatile Synthesis of Functionalized Pentahelicenes
Author(s)	Songis, Olivier (UOCHB-X) Míšek, Jiří (UOCHB-X) Schmid, Markus B. (UOCHB-X) Kollárovič, Adrian (UOCHB-X) Stará, Irena G. (UOCHB-X)_{RID, ORCID} Šaman, David (UOCHB-X)_{RID, ORCID} Císařová, I. (CZ) Starý, Ivo (UOCHB-X)_{RID, ORCID}
Number of authors	8
Source Title	Journal of Organic Chemistry. - : American Chemical Society - ISSN 0022-3263 Roč. 75, č. 20 (2010), s. 6889-6899
Number of pages	11 s.
Language	eng - English
Country	US - United States
Keywords	functionalized pentahelicene ; synthesis ; Suzuki-Miyaura coupling
Subject RIV	CC - Organic Chemistry
R&D Projects	IAA400550916 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	LC512 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
UT WOS	000282604900017
DOI	10.1021/jo1013977
Annotation	A general synthetic methodology for the preparation of functionalized (hetero)helicenes has been developed. It employs the sequence of a double propargyl organometallics (Li, Mg, Ga/In) addition to a tolan-2,2'-dialdehyde-type intermediate, a cobalt-catalyzed [2 + 2 + 2] cycloisomerization of a triyne intermediate, and a double silica gel-assisted acetic acid elimination to receive pentahelicene followed by palladium catalyzed Suzuki-Miyaura coupling.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2011

Number of the records: 1