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Absence of Microbiota (Germ-Free Conditions) Accelerates the Atherosclerosis in ApoE-Deficient Mice Fed Standard Low Cholesterol Diet

SYSNO ASEP	0352895
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Absence of Microbiota (Germ-Free Conditions) Accelerates the Atherosclerosis in ApoE-Deficient Mice Fed Standard Low Cholesterol Diet
Author(s)	Štěpánková, Renata (MBU-M)_RID Tonar, Z. (CZ) Bártová, J. (CZ) Nedorost, L. (CZ) Rossmann, Pavel (MBU-M) Poledne, R. (CZ) Schwarzer, Martin (MBU-M)_{ORCID, RID} Tlaskalová-Hogenová, Helena (MBU-M)_{RID, ORCID}
Source Title	Journal of Atherosclerosis and Thrombosis - ISSN 1340-3478 Roč. 17, č. 8 (2010), s. 796-804
Number of pages	9 s.
Language	eng - English
Country	JP - Japan
Keywords	Germ-free mice ; Commensal bacteria ; Atherogenesis
Subject RIV	EC - Immunology
R&D Projects	NS9775 GA MZd - Ministry of Health (MZ)
	GA303/08/0367 GA ČR - Czech Science Foundation (CSF)
	GA305/08/0535 GA ČR - Czech Science Foundation (CSF)
	1QS500200572 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	2B06155 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z50200510 - MBU-M (2005-2011)
UT WOS	000282824400003
DOI	-
Annotation	The aim of our work was to determine the influence of intestinal bacteria on the development of atherosclerotic lesions using apolipoprotein E (ApoE)-deficient knockout mice. The experiments were performed on ApoE deficient mouse strain C57BL/6, bred under germ-free (GF) conditions for two generations or under conventional conditions with defined microflora (CV).
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2011

Number of the records: 1