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Enzymatic Processing of Bioactive Glycosides from Natural Sources
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SYSNO ASEP 0352319 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Enzymatic Processing of Bioactive Glycosides from Natural Sources Author(s) Weignerová, Lenka (MBU-M) RID
Křen, Vladimír (MBU-M) RID, ORCIDSource Title Topics in Current Chemistry - ISSN 0340-1022
Roč. 295, - (2010), s. 121-146Number of pages 26 s. Language eng - English Country DE - Germany Keywords alkaloids ; anthocyanidins aroma ; cardioglycosides Subject RIV CC - Organic Chemistry R&D Projects OC09045 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50200510 - MBU-M (2005-2011) UT WOS 000284109400005 DOI 10.1007/128_2010_51 Annotation A number of biologically active natural products are glycosides. Often, the glycosidic residue is crucial for their activity. In other cases, glycosylation only improves their pharmacokinetic parameters. Enzymatic modification of these glycosides– both extension of the glykoside moiety and its selective trimming – is advantageous due to their selectivity and mildness of the reaction conditions in the presence of reactive and sensitive complex aglycones. Enzymatic reactions enable the resulting products to be used as natural products, e.g., in nutraceuticals. This chapter concentrates on naturally occurring glycosides used in medicine but also in the food and flavor industry (e.g., sweeteners). Both classical and modern methods will be discussed Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2011
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