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Modeling of nucleolar self-assembly

SYSNO ASEP	0351861
Document Type	C - Proceedings Paper (int. conf.)
R&D Document Type	Conference Paper
Title	Modeling of nucleolar self-assembly
Author(s)	Blažíková, Michaela (UEM-P) Heřman, P. (CZ) Malínský, Jan (UEM-P)_{RID, ORCID}
Source Title	MS'10 Prague. - Prague : Czech Technical University, 2010 - ISBN 978-80-01-04574-9
Pages	s. 34-37
Number of pages	4 s.
Action	Proceedings of the International Conference on Modelling and Simulation 2010
Event date	22.06.2010-25.06.2010
VEvent location	Praha
Country	CZ - Czech Republic
Event type	EUR
Language	eng - English
Country	CZ - Czech Republic
Keywords	Monte Carlo simulations
Subject RIV	EB - Genetics ; Molecular Biology
R&D Projects	GA204/07/0133 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z50390512 - UEM-P (2005-2011)
UT WOS	000324148500007
Annotation	Mammalian cell nucleoli disassemble at the beginning of mitosis and reassemble again during telophase and the early G1. Dynamics of this process was studied using a model based on entropy driven self-assembly of pre-ribosomal particles generated in a single biosynthetic source. Monte Carlo simulations revealed that such model can explain formation of a large aggregate, a nucleolus, in the vicinity of the source. We examined influence of nucleoplasm properties on dynamics of the aggregate formation.
Workplace	Institute of Experimental Medicine
Contact	Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
Year of Publishing	2011

Number of the records: 1