Number of the records: 1

Singlet Oxygen Imaging in Polymeric Nanofibers by Delayed Fluorescence

SYSNO ASEP	0351766
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Singlet Oxygen Imaging in Polymeric Nanofibers by Delayed Fluorescence
Author(s)	Mosinger, J. (CZ) Lang, Kamil (UACH-T)_{SAI, RID, ORCID} Hostomský, Jiří (UACH-T) Franc, Jiří (UFCH-W) Sýkora, Jan (UFCH-W)_RID Hof, Martin (UFCH-W)_{RID, ORCID} Kubát, Pavel (UFCH-W)_{RID, ORCID, SAI}
Source Title	Journal of Physical Chemistry B. - : American Chemical Society - ISSN 1520-6106 Roč. 114, č. 48 (2010), s. 15773-15779
Number of pages	7 s.
Language	eng - English
Country	US - United States
Keywords	molecular-oxygen ; meso-tetralylporphyrins ; photodynamic therapy
Subject RIV	CA - Inorganic Chemistry
R&D Projects	GA203/08/0831 GA ČR - Czech Science Foundation (CSF)
	GAP208/10/1678 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z40320502 - UACH-T (2005-2011)
	AV0Z40400503 - UFCH-W (2005-2011)
UT WOS	000284738800006
DOI	10.1021/jp105789p
Annotation	Polymeric nanofiber materials loaded with photosensitizers exhibit significant antibacterial activity due to their generation of cytotoxic singlet oxygen O2(1Δg). A time-gated fluorescence imaging technique was used to monitor the photosensitized processes in polystyrene (PS) and gelatin (GE) nanofibers loaded with 0.1 wt % tetraphenylporphyrin (TPP) photosensitizer. The fluorescence decay of TPP at the periphery of the PS nanofibers was single exponential. Increased fluorescence quenching was observed in the domains with higher TPP loading, located in the center of the nanofibers, and added a shorter lifetime component to the kinetics. The domains exhibiting singlet oxygen activity within the nanofibers were visualized and analyzed by singlet oxygen-sensitized delayed fluorescence imaging (SODF). Whereas O2(1Δg) was produced in PS nanofibers, its production in GE nanofibers was limited. These results were confirmed by time-resolved phosphorescence measurements at 1270 nm.
Workplace	Institute of Inorganic Chemistry
Contact	Jana Kroneislová, krone@iic.cas.cz, Tel.: 311 236 931
Year of Publishing	2011

Number of the records: 1