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Oxidative cleavage of 3beta-acetoxy-21-oxolup-18-en-28-oic acid by ruthenium tetroxide
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SYSNO ASEP 0351597 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Oxidative cleavage of 3beta-acetoxy-21-oxolup-18-en-28-oic acid by ruthenium tetroxide Author(s) Kvasnica, Miroslav (UOCHB-X) RID
Spáčilová, Pavla (UOCHB-X) RID, ORCID
Buděšínský, Miloš (UOCHB-X) RID, ORCID
Hajdúch, M. (CZ)
Sarek, J. (CZ)Number of authors 5 Source Title Chemistry of Natural Compounds - ISSN 0009-3130
Roč. 46, č. 4 (2010), s. 545-548Number of pages 4 s. Language eng - English Country UZ - Uzbekistan Keywords lupane triterpenoids ; oxidation ; ruthenium tetroxide ; cleavage ; decarboxylation Subject RIV CC - Organic Chemistry CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000284876100009 DOI 10.1007/s10600-010-9672-8 Annotation 3Acetoxy-21-oxolup-18-en-28-oic acid was used for oxidative cleavage by ruthenium tetroxide in a biphasic system. Tricyclic and tetracyclic acids and their derivatives were prepared. All prepared compounds were tested on cytotoxic activity against CEM tumor cell. Some of them showed activity in low micromolar concentrations. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2011
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