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Comparative Ultrastructure of Langerhans-Like Cells in Spleens of Ray-Finned Fishes (Actinopterygii)

SYSNO ASEP	0350374
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Comparative Ultrastructure of Langerhans-Like Cells in Spleens of Ray-Finned Fishes (Actinopterygii)
Author(s)	Lovy, J. (CA) Wright, G. M. (CA) Speare, D. J. (CA) Tyml, Tomáš (BC-A) Dyková, Iva (BC-A)_RID
Source Title	Journal of Morphology - ISSN 0362-2525 Roč. 271, č. 10 (2010), s. 1229-1239
Number of pages	11 s.
Language	eng - English
Country	US - United States
Keywords	fish ; cyprinidae ; halibut ; dendritic cells ; Langerhans cell ; Birbeck granules ; ultrastructure
Subject RIV	GJ - Animal Vermins ; Diseases, Veterinary Medicine
R&D Projects	LC522 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z60220518 - PAU-O, BC-A (2005-2011)
UT WOS	000282407000007
DOI	10.1002/jmor.10866
Annotation	We studied the morphology and occurrence of splenic Langerhans-like (LL) cells in species representing 11 orders of ray-finned fishes, Actinopterygii. LL cells were frequent in spleen tissue of species among Cypriniformes, Esociformes, Salmoniformes, and Pleuronectiformes. These cells contained granules which resembled Birbeck granules known to occur in mammalian Langerhans cells. The ultrastructure of BL granules across the species is discussed. Additionally, multivesicular bodies were present within the cytoplasm and large aggregates of exosomes were observed closely associated with the plasma membrane suggesting their release from the cells. These structures are discussed in relation to mammalian dendritic cells. Macrophages found in some species contained lysosomes and residual bodies with structures resembling Birbeck granules. These granules and cells were clearly distinct from LL cells.
Workplace	Biology Centre (since 2006)
Contact	Dana Hypšová, eje@eje.cz, Tel.: 387 775 214
Year of Publishing	2011

Number of the records: 1