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Exposure to air pollution in critical prenatal time windows and IgE levels in newborns

SYSNO ASEP	0350213
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Exposure to air pollution in critical prenatal time windows and IgE levels in newborns
Author(s)	Herr, C.E.W. (US) Grosh, R. (US) Dostál, Miroslav (UEM-P)_RID Skokanová, V. (CZ) Ashwood, P. (US) Lipsett, M. (US) Joad, J.P. (US) Pinkerton, K.E. (US) Yap, P.S. (US) Frost, J. D. (US) Šrám, Radim (UEM-P)_RID Hertz-Picciotto, I. (US)
Source Title	Pediatric Allergy and Immunology - ISSN 0905-6157 Roč. 22, č. 1 (2011), s. 75-84
Number of pages	10 s.
Language	eng - English
Country	DK - Denmark
Keywords	immunoglobulin ; developmental immunology ; pregnancy
Subject RIV	DN - Health Impact of the Environment Quality
R&D Projects	SP/1B3/8/08 GA MŽP - Ministry of Environment (MŽP)
CEZ	AV0Z50390512 - UEM-P (2005-2011)
UT WOS	000287319500012
EID SCOPUS	78851470139
DOI	10.1111/j.1399-3038.2010.01074.x
Annotation	The association between elevated cord serum IgE levels and maternal air pollution exposure during each month of gestation was analyzed. Total cord serum IgE was determined by the CAP system and mother´s total IgE levels by nephelometry for 459 births (from Mar 1994 to Jan. 1997) in the Czech Rep. Conc. of PAHs and particulate matter (PM2,5) were measured in ambient air, and arithmetic means were calculated for each gestational month. Heterogeneity by maternal atopy status was evaluated for air pollutants and cigarette smoke. In was found that PAHs and PM2,5 constituents of both ambient air and cigarette smoke appear to influence fetal immune development, particularly among infants whose mothers are not atopic.
Workplace	Institute of Experimental Medicine
Contact	Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218
Year of Publishing	2013

Number of the records: 1