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Effects of damage to auditory cortex on the discrimination of speech sounds by rats
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SYSNO ASEP 0349290 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Effects of damage to auditory cortex on the discrimination of speech sounds by rats Author(s) Floody, O. R. (US)
Ouda, Ladislav (UEM-P) RID
Porter, B. A. (US)
Kilgard, M. P. (US)Source Title Physiology and Behavior. - : Elsevier - ISSN 0031-9384
Roč. 101, č. 2 (2010), s. 260-268Number of pages 9 s. Language eng - English Country US - United States Keywords auditory cortex ; brain lesions ; prepulse inhibition Subject RIV FH - Neurology R&D Projects GA309/07/1336 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50390703 - UEM-P (2007-2013) UT WOS 000281271400009 DOI 10.1016/j.physbeh.2010.05.009 Annotation The intensity of a noise-induced startle response can be reduced by the presentation of a stimulus immediately before the noise (“prepulse inhibition” or PPI). We used a form of PPI to study the effects of endothelin-induced damage to auditory cortex on the discrimination of human speech sounds by rats. The analysis of individual differences in performance by multiple regression suggests that some of the temporal processing required to discriminate speech sounds is concentrated anteroventrally in the right A1. These results also confirm that PPI can be adapted to studies of the brain mechanisms involved in the processing of speech and other complex sounds. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2011
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