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Analysis of In Vitro and In Vivo Characteristics of Human Embryonic Stem Cell-Derived Neural Precursors
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SYSNO ASEP 0348933 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Analysis of In Vitro and In Vivo Characteristics of Human Embryonic Stem Cell-Derived Neural Precursors Author(s) Kozubenko, Nataliya (UEM-P) RID
Turnovcová, Karolína (UEM-P) ORCID
Kapcalová, Miroslava (UEM-P)
Butenko, Olena (UEM-P)
Anděrová, Miroslava (UEM-P) RID, ORCID
Rusňáková, Vendula (BTO-N)
Kubista, Mikael (BTO-N) RID
Hampl, Aleš (UEM-P)
Jendelová, Pavla (UEM-P) RID, ORCID
Syková, Eva (UEM-P) RIDSource Title Cell Transplantation. - : Sage - ISSN 0963-6897
Roč. 19, č. 4 (2010), s. 471-486Number of pages 16 s. Language eng - English Country US - United States Keywords Human embryonic stem cells (hESCs) ; Fluorescent-activated cell sorting ; Neural differentiation Subject RIV FH - Neurology R&D Projects LC554 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA305/09/0717 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50390703 - UEM-P (2007-2013) AV0Z50520701 - BTO-N (2007-2013) UT WOS 000278942800009 DOI 10.3727/096368909X484707 Annotation In this article we demonstrate derivation and in vitro and in vivo (after transplantation in the rat model of stroke) analysis of highly enriched and expandable populations of proliferating neural precursors from hESCs. Our results complete the characterization of the CCTL14 line of hESCs and provide a framework for developing cell selection strategies for neural cell-based therapies. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2011
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