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Oligoperoxide based physically detectable nanocomposites for cell targeting, visualization and treatment

SYSNO ASEP	0348482
Document Type	C - Proceedings Paper (int. conf.)
R&D Document Type	Conference Paper
Title	Oligoperoxide based physically detectable nanocomposites for cell targeting, visualization and treatment
Author(s)	Zaichenko, A. S. (UA) Mitina, N. (UA) Shevchuk, O. (UA) Shapoval, P. (UA) Boiko, N. (UA) Bilyy, R. (UA) Stoika, R. (UA) Voloshinovskii, A. (UA) Horák, Daniel (UMCH-V)_{RID, ORCID}
Source Title	AIP Conference Proceedings. - Frascati : American Institute of Physics, 2010 / Borsella E. - ISBN 978-0-7354-0826-5
Pages	s. 178-182
Number of pages	5 s.
Action	BONSAI Project Symposium: Breakthroughs in Nanoparticles for Bio-Imaging
Event date	08.04.2010-09.04.2010
VEvent location	Frascati
Country	IT - Italy
Event type	WRD
Language	eng - English
Country	IT - Italy
Keywords	oligoperoxide surfactants ; oligoelectrolytes ; drug and gene delivery systems
Subject RIV	CD - Macromolecular Chemistry
CEZ	AV0Z40500505 - UMCH-V (2005-2011)
DOI	doi:10.1063/1.3505073
Annotation	Novel promising routes for the obtaining luminescent, magnetic, plasmon resonance capable nanocomposites as well as drug delivery systems are proposed and studied. These routes are based on the synthesis and application of original type of functional oligoperoxides, their coordinating complexes of transition including rare earth metal cations for controlled synthesis of block, comb-like or nanogel oligoelectrolytes as well as for template synthesis of functional polymer and polymer-mineral nanoparticles. Developed nanoscale delivery systems were tested as medicines for cancer administration in vitro and in vivo. Physically detectable lectin-conjugated nanocomposites were studied as biomarkers for pathological cell targeting and visualization.
Workplace	Institute of Macromolecular Chemistry
Contact	Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358
Year of Publishing	2011

Number of the records: 1