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Impact of heat-inactivated Lactobacillus casei and Lactobacillus paracasei strains on cytokine responses in whole blood cell cultures of children with atopic dermatitis

SYSNO ASEP	0348114
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Impact of heat-inactivated Lactobacillus casei and Lactobacillus paracasei strains on cytokine responses in whole blood cell cultures of children with atopic dermatitis
Author(s)	Cukrowska, B. (PL) Rosiak, I. (PL) Klewicka, E. (PL) Motyl, I. (PL) Schwarzer, Martin (MBU-M)_{ORCID, RID} Libudzisz, Z. (PL) Kozáková, Hana (MBU-M)_{RID, ORCID}
Source Title	Folia Microbiologica. - : Springer - ISSN 0015-5632 Roč. 55, č. 3 (2010), s. 277-280
Number of pages	4 s.
Language	eng - English
Country	CZ - Czech Republic
Keywords	lactobacillus casei ; atopic dermatitis ; allergy
Subject RIV	EC - Immunology
R&D Projects	GA303/09/0449 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z50200510 - MBU-M (2005-2011)
UT WOS	000278469400013
DOI	10.1007/s12223-010-0041-6
Annotation	Heat-inactivated Lactobacillus casei LOCK 0900, L. casei LOCK 0908 and Lactobacillus paracasei LOCK 0919 strains, applied to blood cell cultures obtained from children with atopic dermatitis induced production of anti-allergic TH1 and regulatory cytokines but did not stimulate pro-allergic interleukin-5. The lactobacilli-mixture remarkably enhanced the TH1 response compared to single strains. The mixture of Lactobacillus strains represents a probiotic bacterial preparation modulating in vitro cytokine profile of allergic children towards anti-allergic TH1 response
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2011

Number of the records: 1