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Study of rheological and electrical behaviour of RBC suspensions in dextran and PEG under non-steady flow. Role of RBC deformability and morphology
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SYSNO ASEP 0348106 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Study of rheological and electrical behaviour of RBC suspensions in dextran and PEG under non-steady flow. Role of RBC deformability and morphology Author(s) Antonova, N. (BG)
Říha, Pavel (UH-J) SAI, ORCID, RID
Ivanov, I. (BG)
Gluhcheva, Y. (BG)Number of authors 4 Source Title 6th World Congress of Biomechanics (WCB 2010). - Heidelberg : Springer, 2010 / Lim C. T. ; Goh J. C. H. - ISSN 1680-0737 - ISBN 978-3-642-14514-8 Pages s. 330-333 Number of pages 4 s. Publication form CD-ROM - CD-ROM Action WCB 2010: World Congress of Biomechanics /6./ Event date 01.08.2010-06.08.2010 VEvent location Singapore Country SG - Singapore Event type WRD Language eng - English Country DE - Germany Keywords electrorheology ; RBC suspensions in dextrans and PEG solutions ; conductivity ; deformability ; RBC morphology Subject RIV BK - Fluid Dynamics R&D Projects IAA200600803 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z20600510 - UH-J (2005-2011) UT WOS 000306716100085 Annotation The electrical conductivity and shear rate dependences in parallel with the rheological properties of the samples were studied under transient flow regimes at different local structure of the uniform Couette flow. Red blood cells (RBC) were treated with glutaraldehyde (GA) with different concentrations (from 0,01% to 1%). A time course of conductivity of normal RBC and treated with GA suspended in dextran 70 was recorded under trapezoid change of shear rates. It provides experimental description of RBC aggregation-disaggregation processes and other cell-cell interactions. Dextrans induce morphological alterations in RBC shape and arrangement in the suspensions. Echinocytes are observed at low Dx 70 concentrations while spherocytes are found mainly in smears at higher Dx 70 concentrations. Their morphological characteristics affect blood electrical and mechanical properties. Workplace Institute of Hydrodynamics Contact Soňa Hnilicová, hnilicova@ih.cas.cz, Tel.: 233 109 003 Year of Publishing 2011
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