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Pooled analysis of studies on DNA adducts and dietary vitamins
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SYSNO ASEP 0347678 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Pooled analysis of studies on DNA adducts and dietary vitamins Author(s) Ragin, C. (US)
Minor, A. (US)
Agudo, A. (ES)
Farmer, P. (GB)
Garte, S. (IT)
Gonzales, C. (ES)
Kalina, I. (SK)
Matullo, G. (IT)
Popov, T. (BG)
Palli, D. (IT)
Peluso, M. (IT)
Ricceri, F. (IT)
Šrám, Radim (UEM-P) RID
Vineis, P. (GB)
Taioli, E. (US)Source Title Mutation Research-Reviews in Mutation Research. - : Elsevier - ISSN 1383-5742
Roč. 705, č. 2 (2010), s. 77-82Number of pages 6 s. Language eng - English Country NL - Netherlands Keywords biomarkers ; carcinogenicity ; molecular epidemiology Subject RIV DN - Health Impact of the Environment Quality CEZ AV0Z50390512 - UEM-P (2005-2011) UT WOS 000282467600002 EID SCOPUS 77956257119 DOI 10.1016/j.mrrev.2010.04.004 Annotation The study investigates the association between vitamins, DNA adducts environmentally induced by carcinogens, and smoking. It was found that vitamin E was inversely significantly associated with DNA adducts after adjustment for possible confounding factors. Vitamin A and C were not independent predictors of DNA adducts. A stratified analysis showed that vitamin A had a significant inverse association with DNA adducts in ever smokers only. These results are relevant to planning any future chemo-preventive interventions directed to high risk subgroups of the population, for cancer prevention. Workplace Institute of Experimental Medicine Contact Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2011
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