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Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats
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SYSNO ASEP 0347398 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats Author(s) Straková, J. (US)
Williams, K. T. (US)
Gupta, S. (US)
Schalinske, K. L. (US)
Kruger, W. D. (US)
Rozen, R. (CA)
Jiráček, Jiří (UOCHB-X) RID, ORCID
Li, L. (US)
Garrow, T. A. (US)Number of authors 9 Source Title Nutrition Research. - : Elsevier - ISSN 0271-5317
Roč. 30, č. 7 (2010), s. 492-500Number of pages 9 s. Language eng - English Country US - United States Keywords BHMT ; homocysteine ; rat ; betaine Subject RIV CC - Organic Chemistry R&D Projects GAP207/10/1277 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000281701400008 DOI 10.1016/j.nutres.2010.06.017 Annotation In the present study, CBHcy, an inhibitor of BHMT enzyme was fed to rats. CBHcy-mediated BHMT inhibition causes an elevation in total plasma Hcy that is not normalized by the folate-dependent conversion of Hcy to methionine. methionine. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2011
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