Number of the records: 1

TGF-beta1 suppresses IL-6-induced STAT3 activation through regulation of Jak2 expression in prostate epithelial cells

SYSNO ASEP	0347188
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	TGF-beta1 suppresses IL-6-induced STAT3 activation through regulation of Jak2 expression in prostate epithelial cells
Author(s)	Staršíchová, Andrea (BFU-R) Lincová, Eva (BFU-R) Pernicová, Zuzana (BFU-R)_RID Kozubík, Alois (BFU-R)_{RID, ORCID} Souček, Karel (BFU-R)_{RID, ORCID}
Number of authors	5
Source Title	Cellular Signalling. - : Elsevier - ISSN 0898-6568 Roč. 22, č. 11 (2010), s. 1734-1744
Number of pages	11 s.
Language	eng - English
Country	US - United States
Keywords	interleukin-6 ; transforming growth factor-beta ; prostate
Subject RIV	BO - Biophysics
R&D Projects	NS9600 GA MZd - Ministry of Health (MZ)
CEZ	AV0Z50040507 - BFU-R (2005-2011)
	AV0Z50040702 - BFU-R (2007-2013)
UT WOS	000281463500016
DOI	10.1016/j.cellsig.2010.06.014
Annotation	Our study demonstrated a novel interaction between TGF-beta1 and IL-6 signalling and suggested another mechanism of how defects in TGF-beta signalling, frequently associated with prostate pathologies, can contribute to the disruption of tissue homeostasis.
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2011

Number of the records: 1