Number of the records: 1

Inhibition of canonical Wnt signaling promotes gliogenesis in PO-NSCs

SYSNO ASEP	0345341
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Inhibition of canonical Wnt signaling promotes gliogenesis in PO-NSCs
Author(s)	Kunke, D. (NO) Bryja, Vítězslav (BFU-R)_{RID, ORCID} Mygland, L. (NO) Arenas, E. (SE) Krauss, S. (NO)
Number of authors	5
Source Title	Biochemical and Biophysical Research Communications. - : Elsevier - ISSN 0006-291X Roč. 386, č. 4 (2009), s. 628-633
Number of pages	6 s.
Language	eng - English
Country	US - United States
Keywords	differentiation ; gliogenesis ; neuronal progenitor cells
Subject RIV	BO - Biophysics
CEZ	AV0Z50040507 - BFU-R (2005-2011)
	AV0Z50040702 - BFU-R (2007-2013)
UT WOS	000268462100016
DOI	10.1016/j.bbrc.2009.06.084
Annotation	Writ signaling plays an essential role in the development of mammalian central nervous system. We investigated the impact of activation/inhibition of the Writ signaling pathway on neuronal/glial differentiation in neurospheres derived from neonatal mouse forebrains. For short term alterations, neurospheres were stimulated with recombinant Wnt-3a, Wnt-5a and the Wnt inhibitor Dickkopf-1 (Dkk1).
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2011

Number of the records: 1