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Growth/differentiation factor-15 inhibits differentiation into osteoclasts - A novel factor involved in control of osteoclast differentiation

SYSNO ASEP	0345304
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Growth/differentiation factor-15 inhibits differentiation into osteoclasts - A novel factor involved in control of osteoclast differentiation
Author(s)	Vaňhara, P. (CZ) Lincová, Eva (BFU-R) Kozubík, Alois (BFU-R)_{RID, ORCID} Jurdic, P. (FR) Souček, Karel (BFU-R)_{RID, ORCID} Šmarda, J. (CZ)
Number of authors	6
Source Title	Differentiation. - : Elsevier - ISSN 0301-4681 Roč. 78, č. 4 (2009), s. 213-222
Number of pages	10 s.
Language	eng - English
Country	DE - Germany
Keywords	osteoclast differentiation ; GDF-15 ; prostate cancer
Subject RIV	BO - Biophysics
R&D Projects	GA204/07/0834 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z50040507 - BFU-R (2005-2011)
	AV0Z50040702 - BFU-R (2007-2013)
UT WOS	000274532600003
DOI	10.1016/j.diff.2009.07.008
Annotation	Both purified GDF-15 and unpurified product secreted by prostate cancer cells strongly intereferes with differentiation of osteoclasts by inhibiting expression and activity of NFkappaB and c-Fos transcription factors.
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2011

Number of the records: 1