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Growth of Vascular Smooth Muscle Cells on Collagen I Exposed to RBL-2H3 Mastocytoma Cells
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SYSNO ASEP 0345062 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Growth of Vascular Smooth Muscle Cells on Collagen I Exposed to RBL-2H3 Mastocytoma Cells Author(s) Maxová, H. (CZ)
Bačáková, Lucie (FGU-C) RID, ORCID
Eckhardt, Adam (FGU-C) RID, ORCID
Mikšík, Ivan (FGU-C) RID, ORCID, SAI
Lisá, Věra (FGU-C)
Novotná, J. (CZ)
Herget, J. (CZ)Source Title Cellular Physiology and Biochemistry. - : Cellular Physiology and Biochemistry - ISSN 1015-8987
Roč. 25, č. 6 (2010), s. 615-622Number of pages 8 s. Language eng - English Country CH - Switzerland Keywords pulmonary hypertension ; collagen degradation ; smooth muscle cell proliferation Subject RIV EI - Biotechnology ; Bionics R&D Projects GA305/08/0108 GA ČR - Czech Science Foundation (CSF) 1M0510 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000277890000006 DOI 10.1159/000315080 Annotation The aim of this “in vitro” study was to verify that mast cells are capable of splitting collagen and then facilitating the growth of vascular smooth muscle cells (VSMC). Increased growth activity of VSMC was probably due to the fragmentation of collagen by proteases released from RBL-2H3 cells. Mast cells exposed to hypoxia are more capable to split collagen and facilitate the gowth of VSMC Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2011
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