Number of the records: 1

Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM

SYSNO ASEP	0344070
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM
Author(s)	Réblová, Kamila (BFU-R) Rázga, Filip (BFU-R) Li, W. (US) Gao, H. (US) Frank, J. (US) Šponer, Jiří (BFU-R)_{RID, ORCID}
Number of authors	6
Source Title	Nucleic Acids Research. - : Oxford University Press - ISSN 0305-1048 Roč. 38, č. 4 (2010), s. 1325-1340
Number of pages	16 s.
Language	eng - English
Country	GB - United Kingdom
Keywords	molecular dynamics ; Cryo-electron microscopy ; RNA
Subject RIV	BO - Biophysics
R&D Projects	LC06030 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	KJB400040901 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	1QS500040581 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	IAA400040802 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	GA203/09/1476 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z50040507 - BFU-R (2005-2011)
	AV0Z50040702 - BFU-R (2007-2013)
UT WOS	000275270500032
DOI	10.1093/nar/gkp1057
Annotation	We carried out molecular dynamics simulations of the base of the A-site finger from archaeal and three bacterial large subunits. The study showed that despite noticeable differences in the secondary structures, the studied segments adopt almost identical fold and exhibit similar stochastic fluctuations. Geometries of segments from the simulations correspond to structures obtained by Cryo-electron microscopy.
Workplace	Institute of Biophysics
Contact	Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244
Year of Publishing	2011

Number of the records: 1