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Electrochemistry of selected radiosenzitizer-etanidazole

SYSNO ASEP	0343502
Document Type	C - Proceedings Paper (int. conf.)
R&D Document Type	Conference Paper
Title	Electrochemistry of selected radiosenzitizer-etanidazole
Author(s)	Gál, Miroslav (UFCH-W) Híveš, J. (SK) Sokolová, Romana (UFCH-W)_{RID, ORCID, SAI} Hromadová, Magdaléna (UFCH-W)_{RID, ORCID, SAI} Kocábová, Jana (UFCH-W)_RID Kolivoška, Viliam (UFCH-W)_{RID, ORCID} Pospíšil, Lubomír (UFCH-W)_{RID, ORCID}
Source Title	Sborník přednášek. XXX. Moderní elektroanalytické metody. - Ústí nad Labem : BEST servis, 2010 / Navrátil Tomáš ; Barek J. - ISBN 978-80-254-6710-7
Pages	s. 55-59
Number of pages	5 s.
Action	Modern Electroanalytical Methods /30./
Event date	24.05.2010-28.05.2010
VEvent location	Jetřichovice
Country	CZ - Czech Republic
Event type	EUR
Language	eng - English
Country	CZ - Czech Republic
Keywords	etanidazole ; cyclic voltammetry ; radiosensitizers ; electrochemical impendance spectroscopy
Subject RIV	CG - Electrochemistry
R&D Projects	GP203/09/P502 GA ČR - Czech Science Foundation (CSF)
	LC510 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	OC 140 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z40400503 - UFCH-W (2005-2011)
UT WOS	000283050900013
Annotation	The first electron transfer to radiosensitizer etanidazole (ETN) and ETN radical anion formation in buffered aqueous media was studied by means of voltammetric techniques and Electrochemical Impendance Spectroscopy (EIS). The heterogeneous electron transfer rate constant for the first reduction of ETN (radical anion production) k0 for the redox couple and so called E1,7 potential were calculated. The obtained values of k0 and E1,7 potential indicate that ETN compared to some other possible chemical radiosensitizers requires lower energy to accept the first electron during metabolic pathway.
Workplace	J. Heyrovsky Institute of Physical Chemistry
Contact	Michaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196
Year of Publishing	2011

Number of the records: 1