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Preparation of new 18alpha-oleanane alcohols: synthesis, characterization, and cytotoxic activity
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SYSNO ASEP 0343366 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Preparation of new 18alpha-oleanane alcohols: synthesis, characterization, and cytotoxic activity Author(s) Kvasnica, Miroslav (UOCHB-X) RID
Rudovská, I. (CZ)
Hajduch, M. (CZ)
Šarek, J. (CZ)Number of authors 4 Source Title Monatshefte fur Chemie. - : Springer - ISSN 0026-9247
Roč. 141, č. 2 (2010), s. 233-244Number of pages 12 s. Language eng - English Country AT - Austria Keywords reduction ; hydride ; ketone ; configuration ; cytotoxicity Subject RIV CC - Organic Chemistry R&D Projects KAN200200651 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z40550506 - UOCHB-X (2005-2011) UT WOS 000274730600013 DOI 10.1007/s00706-009-0249-9 Annotation New oleanane alcohols and their acetates were prepared using classical reductive reagents (LiA1H4, NaBH4, and B2H6-DMS). These products were tested for cytotoxic activity against T-lymphoblastic leukemia (CEM), human erythromyeloblastoid leukemia (K562), and human melanoma (SK-MEL1) cell lines. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2011
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