Number of the records: 1
Thyroid hormones and cardiac arrhythmias
- 1.
SYSNO ASEP 0343337 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Thyroid hormones and cardiac arrhythmias Author(s) Tribulová, N. (SK)
Knezl, V. (SK)
Shainberg, A. (IL)
Seki, S. (JP)
Soukup, Tomáš (FGU-C) RIDSource Title Vascular Pharmacology. - : Elsevier - ISSN 1537-1891
Roč. 52, 3-4 (2010), s. 102-112Number of pages 11 s. Language eng - English Country US - United States Keywords thyroid hormone ; arrhythmias ; ion channels ; connexin-43 Subject RIV FA - Cardiovascular Diseases incl. Cardiotharic Surgery R&D Projects GA304/08/0256 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000275395700002 DOI 10.1016/j.vph.2009.10.001 Annotation Chronic changes in the amount of circulating thyroid hormone due to thyroid dysfunction or systemic disease result in structural, electrophysiological and Ca2+ handling remodeling, while acute changes may affect basal activity of cardiac cells membrane systems. Consequently, long-term or rapid modulation of sarcolemmal ion channels, Ca2+ cycling proteins and intercellular communicating channels by thyroid hormone may affect heart function as well as susceptibility of the heart to arrhythmias. This aspect including pro- and anti-arrhythmic potential of thyroid hormone is highlighted in this review Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2011
Number of the records: 1