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Melatonin interactions with blood pressure and vascular function during l-NAME-induced hypertension
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SYSNO ASEP 0343240 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Melatonin interactions with blood pressure and vascular function during l-NAME-induced hypertension Author(s) Paulis, L. (DE)
Pecháňová, Olga (FGU-C)
Zicha, Josef (FGU-C) RID, ORCID, SAI
Barta, A. (SK)
Gardlik, R. (SK)
Celec, P. (SK)
Kuneš, Jaroslav (FGU-C) RID, ORCID
Šimko, F. (DE)Source Title Journal of Pineal Research - ISSN 0742-3098
Roč. 48, č. 2 (2010), s. 102-108Number of pages 7 s. Language eng - English Country DK - Denmark Keywords endothelium-derived constricting factor ; melatonin ; nitric oxide Subject RIV FA - Cardiovascular Diseases incl. Cardiotharic Surgery R&D Projects IAA500110902 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000273952400003 DOI 10.1111/j.1600-079X.2009.00732.x Annotation To elucidate the possible role of the nitric oxide (NO) pathway in the hemodynamic actions of melatonin, the effects of this indolamine on vascular function during hypertension induced by NO-synthase (NOS) inhibition were investigated. It is evident that, in addition to the reduction of the oxidative load, the restoration of the NO pathway seems to play an important role in the antihypertensive effect of melatonin Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2011
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