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Dependence of Multidrug Resistance Protein-Mediated Cyclic Nucleotide Efflux on the Background Sodium Conductance
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SYSNO ASEP 0343224 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Dependence of Multidrug Resistance Protein-Mediated Cyclic Nucleotide Efflux on the Background Sodium Conductance Author(s) Kučka, M. (US)
Kretschmannová, K. (US)
Murano, T. (US)
Wu, Ch. P. (US)
Zemková, Hana (FGU-C) RID, ORCID
Ambudkar, S. V. (US)
Stojilkovic, S. S. (US)Source Title Molecular Pharmacology - ISSN 0026-895X
Roč. 77, č. 2 (2010), s. 270-279Number of pages 10 s. Language eng - English Country US - United States Keywords multidrug resistance protein ; cAMP ; anterior pituitary Subject RIV ED - Physiology CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000273725600018 DOI 10.1124/mol.109.059386 Annotation Anterior pituitary cells fire action potentials and release cyclic nucleotides both spontaneously and in response to agonist stimulation. A tetrodotoxin-resistant background Na+ conductance is critical for firing of these action potentials. In these cells, multidrug resistance proteins MRP4 and MRP5 -mediated cyclic nucleotide efflux can be rapidly determined by the background Na+ conductance Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2011
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