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Modified approach for preparing (E)-stilbenes related to resveratrol, and evaluation of their potential immunobiological effects
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SYSNO ASEP 0342940 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Modified approach for preparing (E)-stilbenes related to resveratrol, and evaluation of their potential immunobiological effects Author(s) Šmidrkal, J. (CZ)
Harmatha, Juraj (UOCHB-X) RID, ORCID
Buděšínský, Miloš (UOCHB-X) RID, ORCID
Vokáč, Karel (UOCHB-X)
Zídek, Zdeněk (UEM-P)
Kmoníčková, Eva (UEM-P) RID
Merkl, R. (CZ)
Filip, V. (CZ)Number of authors 8 Source Title Collection of Czechoslovak Chemical Communications. - : Ústav organické chemie a biochemie AV ČR, v. v. i. - ISSN 0010-0765
Roč. 75, č. 2 (2010), s. 175-186Number of pages 12 s. Language eng - English Country CZ - Czech Republic Keywords resveratrol ; pterostilbene ; pinosylvin Subject RIV CC - Organic Chemistry R&D Projects GA203/07/1227 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z40550506 - UOCHB-X (2005-2011) AV0Z50390512 - UEM-P (2005-2011) UT WOS 000277125800003 DOI 10.1135/cccc2009531 Annotation Our approach allowed obtaining largely hydroxy- and methoxystilbenes, formed as (E)-isomers only. The hydroxymethoxystilbenes (as e.g. pterostilbene) were prepared using specific OH protection and deprotection. The method is suitable for preparing such compounds in a large amount. Effects of the obtained stilbenoids on immunobiological responses were tested under in vitro conditions. Workplace Institute of Organic Chemistry and Biochemistry Contact asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434 Year of Publishing 2011
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