Charge transport in DNA oligonucleotides with various base-pairing patterns

Kratochvílová, Irena; Todorciuc, Tatiana; Král, Karel; Němec, Hynek; Bunček, M.; Šebera, Jakub; Záliš, Stanislav; Vokáčová, Zuzana; Sychrovský, Vladimír; Bednárová, Lucie; Mojzeš, P.; Schneider, Bohdan

doi:https://dx.doi.org/10.1021/jp100264v

Number of the records: 1

Charge transport in DNA oligonucleotides with various base-pairing patterns

1.

SYSNO ASEP	0342650
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Charge transport in DNA oligonucleotides with various base-pairing patterns
Author(s)	Kratochvílová, Irena (FZU-D)_{RID, ORCID, SAI} Todorciuc, Tatiana (UMCH-V) Král, Karel (FZU-D)_RID Němec, Hynek (FZU-D)_{RID, ORCID, SAI} Bunček, M. (CZ) Šebera, Jakub (UMCH-V) Záliš, Stanislav (UFCH-W)_{RID, ORCID} Vokáčová, Zuzana (UOCHB-X) Sychrovský, Vladimír (UOCHB-X)_{RID, ORCID} Bednárová, Lucie (UOCHB-X)_{RID, ORCID} Mojzeš, P. (CZ) Schneider, Bohdan (BTO-N)_{RID, ORCID}
Source Title	Journal of Physical Chemistry B. - : American Chemical Society - ISSN 1520-6106 Roč. 114, č. 15 (2010), 5196–5205
Number of pages	10 s.
Language	eng - English
Country	US - United States
Keywords	DNA ; charge transport ; Scanning Tunneling Microscopy
Subject RIV	CC - Organic Chemistry
R&D Projects	GA203/08/1594 GA ČR - Czech Science Foundation (CSF)
	KAN401770651 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	OC 137 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	GA202/07/0643 GA ČR - Czech Science Foundation (CSF)
	IAA400550701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	KAN200100801 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	KAN100400702 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
	GA202/09/0193 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z10100520 - FZU-D (2005-2011)
	AV0Z40500505 - UMCH-V (2005-2011)
	AV0Z40400503 - UFCH-W (2005-2011)
	AV0Z40550506 - UOCHB-X (2005-2011)
	AV0Z50520701 - BTO-N (2007-2013)
UT WOS	000276563000027
DOI	10.1021/jp100264v
Annotation	We combined various experimental (STM, Raman spectroscopy) and theoretical (DFT, MD) approaches to study the relationships between the base-pairing patterns and charge transfer properties in DNA 32-mer duplexes that may be relevant for identification and repair of defects in base pairing of the genetic DNA and for DNA use in nanotechnologies. Studied were two duplexes fully Watson-Crick paired, one mismatched (containing three non-W-C pairs), and three with base pairs chemically removed. The results show that the charge transport varies strongly between these duplexes. The conductivity of the mismatched duplex is considerably lower than that of the W-C-paired one despite that their structural integrity and thermal stability are comparable. Structurally and thermally much less stable abasic duplexes have still lower conductivity, but not markedly different from the mismatched duplex.
Workplace	Institute of Physics
Contact	Kristina Potocká, potocka@fzu.cz, Tel.: 220 318 579
Year of Publishing	2011

Number of the records: 1