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Intramolecular Direct C-H Arylation Approach to Fused Purines. Synthesis of Purino[8,9-f]phenanthridines and 5,6-Dihydropurino[8,9-a]isoquinolines

SYSNO ASEP	0342381
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Intramolecular Direct C-H Arylation Approach to Fused Purines. Synthesis of Purino[8,9-f]phenanthridines and 5,6-Dihydropurino[8,9-a]isoquinolines
Author(s)	Čerňa, Igor (UOCHB-X) Pohl, Radek (UOCHB-X)_{RID, ORCID} Klepetářová, Blanka (UOCHB-X)_{RID, ORCID} Hocek, Michal (UOCHB-X)_{RID, ORCID}
Number of authors	4
Source Title	Journal of Organic Chemistry. - : American Chemical Society - ISSN 0022-3263 Roč. 75, č. 7 (2010), s. 2302-2308
Number of pages	7 s.
Language	eng - English
Country	US - United States
Keywords	purines ; cross-coupling ; fused heterocycles ; C-H activation
Subject RIV	CC - Organic Chemistry
R&D Projects	LC06077 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
UT WOS	000275884400018
DOI	10.1021/jo100111t
Annotation	Intramolecular direct C-H arylations were employed as a key step in the synthesis of hitherto unknown fused purine systems. 13-Substituted purino[8,9-f]phenanthridines were prepared from 9-(2-bromophenyl)purines and 2-bromophenylboronic acid, while 11-substituted 5,6-dihydropurino[8,9-a]isoquinolines from 9-(2-chlorophenethyl)purines.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2011

Number of the records: 1