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Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 7: Methods of preparation and comparison of resulting physical properties

SYSNO ASEP	0342350
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part 7: Methods of preparation and comparison of resulting physical properties
Author(s)	Přádný, Martin (UMCH-V)_RID Šlouf, Miroslav (UMCH-V)_{RID, ORCID} Martinová, L. (CZ) Michálek, Jiří (UMCH-V)_{RID, ORCID}
Source Title	E-Polymers. - : EUROPEAN POLYMER FEDERATION - ISSN 1618-7229 -, 043 (2010), s. 1-12
Number of pages	12 s.
Language	eng - English
Country	FR - France
Keywords	porous hydrogels ; 2-hydroxyethyl methacrylate ; porosity
Subject RIV	CD - Macromolecular Chemistry
R&D Projects	GA304/07/1129 GA ČR - Czech Science Foundation (CSF)
	GA106/09/1000 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z40500505 - UMCH-V (2005-2011)
UT WOS	000276742700001
DOI	10.1515/epoly.2010.10.1.470
Annotation	Five methods of preparation of macroporous hydrogels are described and compared: precipitation polymerization, polymerization in presence of salt, polymerization in presence of gas-releasing compound, lyophilization and electrospinning. Crosslinked copolymers based on 2-hydroxyethyl methacrylate were selected as model hydrogels. Hydrogels were characterized by SEM microscopy, porosity, communicating/non-communicating pore ratio, pore sizes and their distributions. The advantages and drawbacks of the methods of preparation, modification of hydrogel properties, reproducibility and issues related to their preparation are discussed. The most convenient method was preparation in presence of salts. The use of prepared porous hydrogels is intended especially for scaffolds in tissue engineering.
Workplace	Institute of Macromolecular Chemistry
Contact	Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358
Year of Publishing	2011

Number of the records: 1