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Comparative effect of amidated pectin and psyllium on cholesterol homeostasis in rats
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SYSNO ASEP 0342032 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Comparative effect of amidated pectin and psyllium on cholesterol homeostasis in rats Author(s) Marounek, Milan (UZFG-Y) RID
Volek, Z. (CZ)
Skřivanová, E. (CZ)
Tůma, J. (CZ)
Dušková, D. (CZ)Source Title Central European Journal of Biology - ISSN 1895-104X
Roč. 5, č. 3 (2010), s. 299-303Number of pages 5 s. Language eng - English Country PL - Poland Keywords Cholesterol homeostazis ; Pectin ; Psyllium Subject RIV GH - Livestock Nutrition CEZ AV0Z50450515 - UZFG-Y (2005-2011) UT WOS 000276483800002 DOI 10.2478/s11535-010-0014-4 Annotation The effects of amidated pectin and psyllium were compared in rats fed diets supplemented with palm fat and cholesterol at 50 and 10 g/kg, respectively. Amidated pectin and psyllium significantly decreased serum cholesterol from 3.41 μmol/ml to 1.68 and 2.04 μmol/ml, respectively, and hepatic cholesterol from 31.9 μmol/g to 7.2 and 9.0 μmol/g, respectively. Faecal cholesterol content was significantly increased in rats that were fed amidated pectin, and non-significantly increased in rats that were fed psyllium. In conclusion, amidated pectin, a novel sequestrant of sterols, demonstrated a similar effect on rat serum and hepatic cholesterol concentration to psyllium, which is a well-established hypocholesterolaemic agent. Workplace Institute of Animal Physiology and Genetics Contact Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Year of Publishing 2011
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