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Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain
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SYSNO ASEP 0341847 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain Author(s) Drahota, Zdeněk (FGU-C) RID, ORCID
Vrbacký, Marek (FGU-C) RID, ORCID
Nůsková, Hana (FGU-C) RID, ORCID
Kazdová, L. (CZ)
Zídek, Václav (FGU-C) RID
Landa, Vladimír (FGU-C) RID
Pravenec, Michal (FGU-C) RID, ORCID
Houštěk, Josef (FGU-C) RID, ORCIDSource Title Biochemical and Biophysical Research Communications. - : Elsevier - ISSN 0006-291X
Roč. 391, č. 3 (2010), s. 1348-1351Number of pages 4 s. Language eng - English Country US - United States Keywords CD36 ; mitochondria ; SSO Subject RIV CE - Biochemistry R&D Projects OC08017 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) NR9387 GA MZd - Ministry of Health (MZ) 1M0520 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA301/08/0166 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000274097800009 DOI 10.1016/j.bbrc.2009.12.050 Annotation We investigated effect of SSO on mitochondrial respiration. Experiments in rat liver, heart and kidney mitochondria demonstrated a direct effect on mitochondrial respiratory chain with the most pronounced inhibition of the complex III. The results show that SSO is a potent and irreversible inhibitor of mitochondrial respiratory chain Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2011
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