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Surface plasmon resonance biosensors for detection of Alzheimer disease biomarkers
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SYSNO ASEP 0341069 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Surface plasmon resonance biosensors for detection of Alzheimer disease biomarkers Author(s) Hegnerová, Kateřina (URE-Y)
Bocková, Markéta (URE-Y)
Vaisocherová, Hana (URE-Y) RID
Krištofíková, Z. (CZ)
Říčný, J. (CZ)
Řípová, D. (CZ)
Homola, Jiří (URE-Y) RIDSource Title Sensors and Actuators B - Chemical. - : Elsevier
Roč. 139, č. 1 (2009), s. 69-73Number of pages 5 s. Language eng - English Country CH - Switzerland Keywords Alzheimer disease ; SPR sensor ; 17beta-HSD10 Subject RIV JB - Sensors, Measurment, Regulation R&D Projects NR9322 GA MZd - Ministry of Health (MZ) KAN200670701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z20670512 - URE-Y (2005-2011) UT WOS 000266429400013 Annotation This paper describes direct label-free detection of 17beta-HSD10 enzyme using a surface plasmon resonance (SPR) biosensor. This multifunctional mitochondrial enzyme is involved in pathogenesis of Alzheimer disease (AD) and represents a potential target for AD diagnostics. It is demonstrated that the reported SPR biosensor is capable of detecting 17beta-HSD10 enzyme at ng/ml levels. Workplace Institute of Radio Engineering and Electronics Contact Petr Vacek, vacek@ufe.cz, Tel.: 266 773 413, 266 773 438, 266 773 488 Year of Publishing 2010
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