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Bendiocarb effect on liver and central nervous system in the chick embryo
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SYSNO ASEP 0340859 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Bendiocarb effect on liver and central nervous system in the chick embryo Author(s) Petrovová, E. (SK)
Sedmera, David (UZFG-Y)
Lešník, František (UZFG-Y)
Luptáková, L. (SK)Source Title Journal of Environmental Science and Health Part B-Pesticides Food Contaminants and Agricultural Wastes. - : Taylor & Francis - ISSN 0360-1234
Roč. 44, č. 4 (2009), s. 383-388Number of pages 6 s. Language eng - English Country US - United States Keywords Bendiocarb ; Chick embryo ; Toxicity Subject RIV EA - Cell Biology CEZ AV0Z50450515 - UZFG-Y (2005-2011) UT WOS 000265334700009 DOI 10.1080/03601230902801091 Annotation The aim of the study was to investigate toxicity of bendiocarb (2, 3-isopropyledene-dioxyphenyl methylcarbamate) to organs of chicken embryo. The toxic action of bendiocarb was observed on liver and central nervous system (CNS). Bendiocarb was administered to chicken embryos at embryonic day (ED) 3 in a dose 500 g/egg and 10 ED (800 g/egg). The observations showed no macroscopic or microscopic changes in the liver and CNS with either dose or day of incubation when the bendiocarb was administered.The liver and CNS were also investigated for caspase activity in relation to application of bendiocarb and no differences in the number of cells with caspase immunopositivity were observed in comparison with the control. The results obtained indicate that bendiocarb administered in the respective doses showed no toxicity to investigated organs. Furthermore, both at the early(3 ED)and the later(10 ED)stages of development no increase in numbers of apoptotic cells in chicken embryos was observed. Workplace Institute of Animal Physiology and Genetics Contact Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Year of Publishing 2010
Number of the records: 1