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Old Herborn University Seminar Monograph. 22. Biological Consequences of Host-Microbe Interactions
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SYSNO ASEP 0340781 Document Type M - Monograph Chapter R&D Document Type Monograph Chapter Title The role of gut microflora in mucosal tolerance induction to birch pollen in mouse allergy model Author(s) Kozáková, Hana (MBU-M) RID, ORCID
Repa, A. (AT)
Schwarzer, Martin (MBU-M) ORCID, RID
Tlaskalová-Hogenová, Helena (MBU-M) RID, ORCID
Štěpánková, Renata (MBU-M) RID
Hudcovic, Tomáš (MBU-M) RID, ORCID
Wiedermann, U. (AT)Source Title Old Herborn University Seminar Monograph. 22. Biological Consequences of Host-Microbe Interactions. - Herborn : Old Herborn University, 2009 / Heidt P.J. ; Hanson L.A. ; Tlaskalová H. ; Rusch V. - ISBN 3-923022-33-6 Pages s. 11-19 Number of pages 9 s. Number of copy 1500 Number of pages 143 Language eng - English Country DE - Germany Keywords germ-free ; microbiota ; birch pollen Subject RIV EC - Immunology R&D Projects IAA500200710 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) 1QS500200572 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) GA303/06/0974 GA ČR - Czech Science Foundation (CSF) GA303/08/0367 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50200510 - MBU-M (2005-2011) Annotation Using germ-free and Lactobacillus plantarum-monocolonized mice we studied the role of microbiota in the development of allergic sensitization and mucosal tolerance induction in a mouse model of type I allergy to birch pollen. In our setting, the absence of the microbiota did not influence the capacity to establish tolerance via the oral or intranasal routes nor to establish an allergic immune response at the humoral or cellular levels Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2010
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