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A myeloperoxidase promoter polymorphism is independently associated with mortality in patients with impaired left ventricular function
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SYSNO ASEP 0340135 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title A myeloperoxidase promoter polymorphism is independently associated with mortality in patients with impaired left ventricular function Author(s) Rudolph, V. (DE)
Rudolph, T.K. (DE)
Kubala, Lukáš (BFU-R) RID, ORCID
Clauberg, N. (DE)
Maas, R. (DE)
Pekarová, Michaela (BFU-R) RID
Klinke, A. (DE)
Lau, D. (DE)
Szöcs, K. (DE)
Meinertz, T. (DE)
Böger, R.H. (DE)
Baldus, S. (DE)Number of authors 12 Source Title Free Radical Biology and Medicine. - : Elsevier - ISSN 0891-5849
Roč. 47, č. 11 (2009), s. 1584-1590Number of pages 7 s. Language eng - English Country US - United States Keywords myeloperoxidase ; heart failure ; free radicals Subject RIV BO - Biophysics R&D Projects GA524/08/1753 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000271934300008 DOI 10.1016/j.freeradbiomed.2009.09.001 Annotation Circulating levels of myeloperoxidase (MPO), a heme enzyme released upon activation of polymorphonuclear neutrophils, predict adverse outcome in patients with impaired left ventricular (LV) function. There is no association of the MPO polymorphism with total MPO protein concentration or MPO activity in plasma. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2010
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