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Comparison of follicular fluid and serum levels of Inhibin A and Inhibin B with calculated indices used as predictive markers of Ovarian Hyperstimulation Syndrome in IVF patients
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SYSNO ASEP 0339716 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Comparison of follicular fluid and serum levels of Inhibin A and Inhibin B with calculated indices used as predictive markers of Ovarian Hyperstimulation Syndrome in IVF patients Author(s) Moos, J. (CZ)
Řežábek, K. (CZ)
Filová, V. (CZ)
Moosová, M. (CZ)
Pavelková, J. (CZ)
Pěknicová, Jana (BTO-N) RIDNumber of authors 6 Source Title Reproductive Biology and Endocrinology. - : BioMed Central
Roč. 86, č. 7 (2009), s. 1-7Number of pages 7 s. Language eng - English Country US - United States Keywords ovarian hyperstimulation syndrome - OHSS ; inhibin A ; inhibin B ; follicular fluid Subject RIV EC - Immunology CEZ AV0Z50520701 - BTO-N (2007-2013) UT WOS 000270144200001 DOI 10.1186/1477-7827-7-86 Annotation Ovarian Hyperstimulation Syndrome (OHSS) is a severe health complication observed in some patients undergoing hormonal stimulation during IVF. Presence of OHSS is often associated with a high count of growing follicles responding to FSH hyperstimulation. However, the number of responding follicles may not be sufficient enough to predict the onset and severity of OHSS. The aim of this study was to find whether follicular fluid (FF) and serum concentrations of Inhibin A and Inhibin B in patients undergoing IVF treatment may serve as a predictor of OHSS status independent of the growing follicles count. Serum Inhibin A and Inhibin B concentrations showed no significant difference between the severe OHSS group and the control group without OHSS. These observations demonstrated that while neither serum nor FF concentrations of Inhibin A or Inhibin B can be used as an OHSS predictor independent of the growing follicle count, calculated indices may meet the criteria. Workplace Institute of Biotechnology Contact Monika Kopřivová, Monika.Koprivova@ibt.cas.cz, Tel.: 325 873 700 Year of Publishing 2010
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