Number of the records: 1

Comparison of in vitro tests for measurement of estrogenity of chlorinated compounds and their use in the evaluation of biodegradation of chlorbenzoates by the fungus Panus tigrinus

SYSNO ASEP	0339618
Document Type	C - Proceedings Paper (int. conf.)
R&D Document Type	Conference Paper
Title	Comparison of in vitro tests for measurement of estrogenity of chlorinated compounds and their use in the evaluation of biodegradation of chlorbenzoates by the fungus Panus tigrinus
Author(s)	Svobodová, Kateřina (MBU-M)_RID Covino, S. (IT) Křesinová, Zdena (MBU-M)_RID Cajthaml, Tomáš (MBU-M)_{RID, ORCID}
Source Title	Odpadové fórum 2009 - sborník přednášek. - Praha : PCHE-PetroChemEng, 2009 - ISBN 978-80-02-02108-7
Pages	s. 3619-3623
Number of pages	5 s.
Action	Odpadové fórum
Event date	22.04.2009-24.04.2009
VEvent location	Milovy
Country	CZ - Czech Republic
Event type	EUR
Language	eng - English
Country	CZ - Czech Republic
Keywords	yeast assay ; biodegradation ; chlorbenzoates
Subject RIV	EE - Microbiology, Virology
R&D Projects	2B06156 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z50200510 - MBU-M (2005-2011)
Annotation	Recently, contamination of the environment by endocrine disruptive compounds, toxicity of these chemicals and their biodegradability are widely studied. This work is focused on estrogenity of chlorinated phenols and chlorbenzoic acids that represent potential degradation products of PCB compounds. Two different yeast bioassays for evaluation of estrogenity based on recombinated strains of Saccharomyces cerevisie were compared in this work. Estrogenic activity of chlorbenzoic acids varied with the chemical structure of chemicals. A mixture of chlorbenzoates (initial concentration 10 ppm) was degraded by a ligninolytic fungus Panus tigrinus in liquid cultures. Chemicals resulting from degradation were tested for their estrogenity, however, results indicated that the test responses were inhibited probably by some compounds present in the fungal culture liquid
Workplace	Institute of Microbiology
Contact	Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
Year of Publishing	2010

Number of the records: 1