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Mechanisms participating in oxidative damage of isolated rat hepatocytes

SYSNO ASEP	0338637
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Mechanisms participating in oxidative damage of isolated rat hepatocytes
Author(s)	Červinková, Z. (CZ) Křiváková, P. (CZ) Lábajová, A. (CZ) Roušar, T. (CZ) Lotková, H. (CZ) Kučera, O. (CZ) Endlicher, R. (CZ) Červinka, M. (CZ) Drahota, Zdeněk (FGU-C)_{RID, ORCID}
Source Title	Archives of Toxicology - ISSN 0340-5761 Roč. 83, č. 4 (2009), s. 363-372
Number of pages	10 s.
Language	eng - English
Country	DE - Germany
Keywords	hepatocytes ; oxidative damage ; mitochondrial enzymes
Subject RIV	CE - Biochemistry
R&D Projects	GA303/06/1261 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z50110509 - FGU-C (2005-2011)
UT WOS	000264883800009
DOI	10.1007/s00204-008-0385-8
Annotation	It was evaluated concentration dependence and time course of the oxidative damage of cytoplasmic membrane and mitochondrial structure and function. It was found that most sensitive indicators of peroxidative damage are changes of mitochondrial membrane potential and oxidation of NADH-dependent substrates
Workplace	Institute of Physiology
Contact	Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
Year of Publishing	2010

Number of the records: 1