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Modification of polylactide surfaces with lactide-ethylene oxide functional block copolymers: Accessibility of functional groups
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SYSNO ASEP 0335741 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Modification of polylactide surfaces with lactide-ethylene oxide functional block copolymers: Accessibility of functional groups Title Modifikace polylaktidových povrchů funkcionalizovanými blokovými kopolymery na bázi laktidu a ethylen oxidu: dostupnost funkčních skupin Author(s) Třesohlavá, Eliška (UMCH-V) RID
Popelka, Štěpán (UMCH-V) RID
Machová, Luďka (UMCH-V) RID
Rypáček, František (UMCH-V) RIDSource Title Biomacromolecules. - : American Chemical Society - ISSN 1525-7797
Roč. 11, č. 1 (2010), s. 68-75Number of pages 8 s. Language eng - English Country US - United States Keywords polylactide ; poly(lactide)-block-poly(ethylene oxide) ; biomimetic Subject RIV CD - Macromolecular Chemistry R&D Projects 1QS500110564 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z40500505 - UMCH-V (2005-2011) UT WOS 000273402500009 DOI 10.1021/bm900889b Annotation Feasibility of using amphiphilic block copolymers composed of polylactide (PLA) and poly(ethylene oxide) (PEO) blocks for biomimetic surface modification of polylactide-based biomaterials for tissue engineering was investigated. PEO-b-PLA copolymers were deposited on the PLA surface from a solution in PEO-selective solvent. Copolymers with a neutral ω-methoxy end group of the PEO block (mPEO-b-PLA) were used to provide hydrophilic surface of PLLA, which exhibited suppressed nonspecific protein adsorption. Workplace Institute of Macromolecular Chemistry Contact Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Year of Publishing 2010
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