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Mitochondrial reticulum network dynamics in relation to oxidative stress, redox regulation, and hypoxia
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SYSNO ASEP 0335307 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Mitochondrial reticulum network dynamics in relation to oxidative stress, redox regulation, and hypoxia Title Dynamika mitochondriální retikulární sítě ve vztahu k oxidativnímu stresu stresu, redoxní regulaci a hypoxii Author(s) Ježek, Petr (FGU-C) RID, ORCID
Plecitá-Hlavatá, Lydie (FGU-C) RID, ORCIDSource Title International Journal of Biochemistry and Cell Biology. - : Elsevier - ISSN 1357-2725
Roč. 41, č. 10 (2009), s. 1790-1804Number of pages 15 s. Language eng - English Country GB - United Kingdom Keywords mitochondria ; network ; mitodynamins Subject RIV CE - Biochemistry R&D Projects IAA500110701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) NR9183 GA MZd - Ministry of Health (MZ) ME09029 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) GA303/07/0105 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50110509 - FGU-C (2005-2011) UT WOS 000270351100006 DOI 10.1016/j.biocel.2009.02.014 Annotation A single mitochondrial network in the cell undergoes constant fission and fusion primarily depending on the local GTP gradients and mitochondrial energetics. In this review are overviewed the main properties and regulation of pro-fusion and pro-fission mitodynamins, i.e. dynamins-related GTPases responsible for mitochondrial shape-forming, such as pro-fusion mitofusins MFN1, MFN2, and the inner membrane-residing long OPA1 isoforms, and pro-fissions mitodynamins FIS1, MFF, and DRP1 multimers required for scission Workplace Institute of Physiology Contact Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Year of Publishing 2010
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