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Molecular detection of Borrelia bissettii DNA in serum samples from patients in the Czech Republic with suspected borreliosis

SYSNO ASEP	0335284
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Molecular detection of Borrelia bissettii DNA in serum samples from patients in the Czech Republic with suspected borreliosis
Author(s)	Rudenko, Natalia (BC-A)_{RID, ORCID} Golovchenko, Maryna (BC-A)_{RID, ORCID} Růžek, Daniel (BC-A)_{RID, ORCID} Piskunova, N. (CZ) Mallátová, N. (CZ) Grubhoffer, Libor (BC-A)_{RID, ORCID}
Source Title	FEMS Microbiology Letters. - : Oxford University Press - ISSN 0378-1097 Roč. 292, č. 2 (2009), s. 274-281
Number of pages	8 s.
Language	eng - English
Country	NL - Netherlands
Keywords	Borrelia bissettii in human serum ; causative agent ; co-infection ; co-detection of different species ; phylogenetic analysis
Subject RIV	GJ - Animal Vermins ; Diseases, Veterinary Medicine
R&D Projects	LC06009 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
	GD524/03/H133 GA ČR - Czech Science Foundation (CSF)
	GA524/06/1479 GA ČR - Czech Science Foundation (CSF)
CEZ	AV0Z60220518 - PAU-O, BC-A (2005-2011)
UT WOS	000263452300017
DOI	10.1111/j.1574-6968.2009.01498.x
Annotation	Until recently, 3 spirochete genospecies were considered to be the causative agents of Lyme borreliosis (LB) in Europe: Borrelia burgdorferi sensu stricto, B. afzelii and B. garinii. However, the DNA of B. valaisiana, B. lusitaniae, B. spielmanii and B. bissettii has already been detected in samples of human origin, or the spirochetes were isolated from the patients with symptoms of LB. Molecular analysis of 12 selected serum samples collected in the regional hospital confirmed the presence of B. bissettii DNA in cases of single and multiple infection in patients with symptomatic borreliosis or chronic borrelial infection. The presence of B. bissettii as a single strain in patients provides strong support of the fact that B. bissettii might be a causative agent of the disease. Here we present additional molecular data supporting the involvement of B. bissettii in LB in Europe.
Workplace	Biology Centre (since 2006)
Contact	Dana Hypšová, eje@eje.cz, Tel.: 387 775 214
Year of Publishing	2010

Number of the records: 1