Number of the records: 1

Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. class III beta-tubulin

SYSNO ASEP	0334046
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. class III beta-tubulin
Author(s)	Katsetos, C.D. (US) Dráberová, Eduarda (UMG-J)_{RID, ORCID} Legido, A. (US) Dumontet, C. (FR) Dráber, Pavel (UMG-J)_{RID, ORCID}
Number of authors	5
Source Title	Journal of Cellular Physiology. - : Wiley - ISSN 0021-9541 Roč. 221, č. 3 (2009), s. 505-513
Number of pages	9 s.
Language	eng - English
Country	US - United States
Keywords	Beta-II-tubulin ; glioblastoma
Subject RIV	EB - Genetics ; Molecular Biology
R&D Projects	KAN200520701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
CEZ	AV0Z50520514 - UMG-J (2005-2011)
UT WOS	000271540100002
DOI	10.1002/jcp.21870
Annotation	This minireview focuses on microtubules and tubulin as emerging targets in potential therapy of GBM using a new class of betaIII-tubulin-targeted drugs in the light of recent developments concerning the function and potential role of this isotype in clinically aggressive tumor behavior, cancer stem cells, tumor hypoxia and chemoresistance to tubulin binding agents, principally taxanes.
Workplace	Institute of Molecular Genetics
Contact	Nikol Škňouřilová, nikol.sknourilova@img.cas.cz, Tel.: 241 063 217
Year of Publishing	2010

Number of the records: 1