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Weight gain associated with atypical and typical antipsychotics during treatment of adolescent schizophrenic psychoses: A retrospective study
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SYSNO ASEP 0333993 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Weight gain associated with atypical and typical antipsychotics during treatment of adolescent schizophrenic psychoses: A retrospective study Title Nárůst hmotnosti spojený s atypickými a typickými antipsychotiky v terapii schizofrenních psychóz adolescentů: retrospektivní studie Author(s) Hrdlička, M. (CZ)
Zedková, I. (CZ)
Blatný, Marek (PSU-E) RID, SAI, ORCID
Urbánek, Tomáš (PSU-E) RID, ORCID, SAINumber of authors 4 Source Title Neuroendocrinology Letters - ISSN 0172-780X
Roč. 30, č. 2 (2009), s. 256-261Number of pages 6 s. Language eng - English Country SE - Sweden Keywords schizophrenia ; antipsychotics ; weight gain Subject RIV AN - Psychology CEZ AV0Z70250504 - PSU-E (2005-2011) UT WOS 000269663900013 Annotation The aim was to assess weight changes associated with atypical (AAP) and typical (TAP) antipsychotics in patients with early-onset schizophrenia and related psychoses. Retrospective study included 109 patients (52 b, 57 g) with a mean age of 15.8 years. The patients were evaluated based to their medical records prior to therapy, then after 1, 3, and 6 weeks of treatment. During the first week of treatment, the AAP group (n = 85) gained 1.5% of baseline weight whereas the TAP group (n = 24) gained only 0.2%. Expressed as absolute values, patients in our sample gained an average of 3.4 kg on AAP and 2.0 kg on TAP during 6 weeks of treatment (n.s.). The patients gained, on average, 3.6 kg on risperidone, 4.4 kg on olanzapine, and 2.1 kg on clozapine during the six weeks of treatment (n.s.). We did not find a difference in weight gain between the AAP and TAP groups, as large as has been described in the literature. Workplace Institute of Psychology Contact Štěpánka Halamová, Halamova@praha.psu.cas.cz, Tel.: 222 222 096 Year of Publishing 2010
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