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Bilateral changes in IL-6 protein, but not in its receptor gp130, in rat dorsal root ganglia following sciatic nerve ligature
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SYSNO ASEP 0333780 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Bilateral changes in IL-6 protein, but not in its receptor gp130, in rat dorsal root ganglia following sciatic nerve ligature Title Bilaterální změny v IL-6 proteinu se zachováním stability jeho receptoru gp130 v kořenových gangliích po ligatuře sedacího nervu Author(s) Brázda, Václav (BFU-R) RID, ORCID
Klusáková, I. (CZ)
Svíženská, I. (CZ)
Veselková, Z. (CZ)
Dubový, P. (CZ)Number of authors 5 Source Title Cellular and Molecular Neurobiology. - : Springer - ISSN 0272-4340
Roč. 29, 6-7 (2009), s. 1053-1062Number of pages 10 s. Language eng - English Country NL - Netherlands Keywords unilateral nerve injury ; neuropathic pain ; IL-6 signaling Subject RIV BO - Biophysics CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000268482300032 DOI 10.1007/s10571-009-9396-0 Annotation Local intracellular signaling cascades following peripheral nerve injury lead to robust axon regeneration and neuropathic pain induction. Cytokines are classic injury-induced mediators. We used sciatic nerve ligature (ScNL) to investigate temporal changes in IL-6 and its receptor gp130 in both ipsilateral and contralateral lumbal (L4-L5) dorsal root ganglia (DRG). Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2010
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