Number of the records: 1  

The central region of BRCA1 binds preferentially to supercoiled DNA

  1. 1.
    SYSNO ASEP0333779
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitleThe central region of BRCA1 binds preferentially to supercoiled DNA
    TitleCentrální doména proteinu BRCA1 se váže preferenčně na superhelikální DNA
    Author(s) Brázda, Václav (BFU-R) RID, ORCID
    Brázdová Jagelská, Eva (BFU-R) RID, ORCID
    Liao, J.C.C. (CA)
    Arrowsmith, Ch.H. (CA)
    Number of authors4
    Source TitleJournal of Biomolecular Structure & Dynamics. - : Taylor & Francis - ISSN 0739-1102
    Roč. 27, č. 1 (2009), s. 97-103
    Number of pages7 s.
    Languageeng - English
    CountryUS - United States
    KeywordsBRCA1 protein ; DNA binding ; protein-DNA complex
    Subject RIVBO - Biophysics
    R&D ProjectsGP301/07/P160 GA ČR - Czech Science Foundation (CSF)
    LC06035 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
    IAA500040701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR)
    CEZAV0Z50040507 - BFU-R (2005-2011)
    AV0Z50040702 - BFU-R (2007-2013)
    UT WOS000268075200009
    DOI-
    AnnotationBRCA1 is a multifunctional tumor suppressor protein with implications in regulating processes such as cell cycle, transcription, DNA repair and chromatin remodeling with preferential binding on superhelical DNA.
    WorkplaceInstitute of Biophysics
    ContactJana Poláková, polakova@ibp.cz, Tel.: 541 517 244
    Year of Publishing2010
Number of the records: 1  

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