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The central region of BRCA1 binds preferentially to supercoiled DNA
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SYSNO ASEP 0333779 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title The central region of BRCA1 binds preferentially to supercoiled DNA Title Centrální doména proteinu BRCA1 se váže preferenčně na superhelikální DNA Author(s) Brázda, Václav (BFU-R) RID, ORCID
Brázdová Jagelská, Eva (BFU-R) RID, ORCID
Liao, J.C.C. (CA)
Arrowsmith, Ch.H. (CA)Number of authors 4 Source Title Journal of Biomolecular Structure & Dynamics. - : Taylor & Francis - ISSN 0739-1102
Roč. 27, č. 1 (2009), s. 97-103Number of pages 7 s. Language eng - English Country US - United States Keywords BRCA1 protein ; DNA binding ; protein-DNA complex Subject RIV BO - Biophysics R&D Projects GP301/07/P160 GA ČR - Czech Science Foundation (CSF) LC06035 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) IAA500040701 GA AV ČR - Academy of Sciences of the Czech Republic (AV ČR) CEZ AV0Z50040507 - BFU-R (2005-2011) AV0Z50040702 - BFU-R (2007-2013) UT WOS 000268075200009 DOI - Annotation BRCA1 is a multifunctional tumor suppressor protein with implications in regulating processes such as cell cycle, transcription, DNA repair and chromatin remodeling with preferential binding on superhelical DNA. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2010
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